Rhodium(III)-catalyzed annulation for the construction of indolizinone and quinolizinone scaffolds through C(sp<SP>2)-H activation

Promovendus/a: Liangliang Song

Promotor(en): Prof. dr. Erik Van der Eycken

This research focuses on several explorations of the construction of indolizinone and quinolizinone scaffolds through rhodium(III)-catalyzed C(sp2)-H activation followed by annulation with alkynes. Based on the understanding of transition metal-catalyzed C-H activation, as well as knowing the significance of indolizinone and quinolizinone scaffolds, the possibility of combining them is investigated. By different designs of substrate structures, indolizinone and quinolizinone scaffolds could be synthesized in different ways.